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How often must an IRB renew its registration?

  1. Every year

  2. Every 2 years

  3. Every 3 years

  4. Every 5 years

The correct answer is: Every 3 years

Research involving human subjects is subject to review by an Institutional Review Board (IRB). IRBs must register with the federal government and must renew their registration every three years. Options A and D are incorrect because one year is too frequent and five years is too infrequent for an IRB to renew its registration. Option B is incorrect because it appears to be a compromise answer between the two extremes, but it does not match the actual requirement of every three years. Therefore, option C is the most accurate answer.